growth-hormone
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growth-hormone
AOD-9604 10mg
For in vitro research only
A modified C-terminal fragment of human growth hormone (hGH 176-191 with an N-terminal tyrosine) supplied as a 10 mg lyophilized vial for research into lipolysis, fat metabolism, and growth-hormone-fragment signaling.
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$85.78
Quantity
1
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Advanced lab tests
HPLC tests
Endotoxin assay
TYMC test
TAMC test
Heavy metals screening
Technical specification
- Molecular formula
- C₇₈H₁₂₃N₂₃O₂₃S₂
- Molar mass
- 1815.1 g/mol
- Purity
- ≥99%
- Synonyms
- hGH fragment 176-191 (Tyr), AOD9604, CAS 221231-10-3
- Solubility
- Water-soluble (reconstitute with bacteriostatic water)
- Organoleptic profile
- White to off-white lyophilized powder
- Composition
- Synthetic peptide — requires reconstitution
Key attributes
Kit contents
- 1 × AOD-9604 10mg vial
- Tamper-evident flip-off cap
- Batch-tested for purity (≥99%)
- Lyophilized for stability during shipping
Each vial is intended for laboratory research use only and is not for human or veterinary use.
Research usage
How is AOD-9604 10mg used in research?
AOD-9604 is investigated as a modified C-terminal fragment of human growth hormone, corresponding to residues 176-191 with a tyrosine added at the N-terminus. In preclinical models it is studied for lipolytic and anti-lipogenic activity, with research probing how the fragment may influence the mobilization and breakdown of stored lipids. A central research question is whether AOD-9604 can modulate fat metabolism independently of the growth-promoting portion of the parent hormone. Investigators use it to explore signaling pathways associated with adipose tissue and energy balance in cell and animal systems. It is frequently examined alongside other growth-hormone-derived fragments to compare metabolic activity profiles.
Research reports that AOD-9604 can stimulate lipolysis and reduce lipogenesis in adipose tissue preparations, effects observed in vitro and in animal research models. Published studies note that these metabolic actions were reported without the increases in IGF-1 or the changes in glucose handling typically associated with intact growth hormone. In rodent obesity models, investigators have documented reductions in body-fat measures following administration in the experimental protocols studied. Some reports also examine the fragment's stability and its interaction with lipid-metabolism pathways. These findings are confined to laboratory and preclinical research contexts and are not conclusions about any human outcome.
The safety and toxicological profile of AOD-9604 has not been completely characterized. This material is supplied strictly for in-vitro and preclinical laboratory research and must be handled only by qualified personnel using appropriate protective equipment. It is not a drug, food, or cosmetic and is not for human or veterinary use. Store securely, keep away from unauthorized access, and dispose of according to applicable laboratory waste regulations.
Recommended ratio
- 2 mL of bacteriostatic water per 10 mg vial
- Equivalent to 5 mg/mL (i.e. 0.5 mg per 10 units on a 100 U insulin syringe)
- Disinfect the vial stopper with an alcohol swab and let it dry.
- Inject the bacteriostatic water slowly down the inner wall of the vial, avoiding a direct stream onto the powder.
- Gently swirl — do not shake — until the solution is clear, then store as directed below.
Unopened / before reconstitution
- Store refrigerated (2 °C – 8 °C), protected from light and moisture.
- For long-term storage, keep frozen (-20 °C); the lyophilized powder remains stable for extended periods.
Reconstituted solution
- Store refrigerated (2 °C – 8 °C) and use within the research period, typically up to 2–4 weeks.
- Avoid repeated freeze-thaw cycles; aliquot if long-term storage of the solution is required.
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