TB-500
TB-500 10mg
$84.64
TB-500
TB-500 5mg
For in vitro research only
A synthetic thymosin β4-derived peptide supplied as a 5 mg lyophilized vial for research into actin binding and sequestration, cell migration, angiogenesis, and tissue repair.
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$50.33
Size
5mg10mg
Quantity
1
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Endotoxin assay
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Technical specification
- Molecular formula
- -
- Molar mass
- -
- Purity
- ≥99%
- Synonyms
- Thymosin β4 (TB-500); CAS 77591-33-4
- Solubility
- Water-soluble (reconstitute with bacteriostatic water)
- Organoleptic profile
- White to off-white lyophilized powder
- Composition
- Synthetic peptide — requires reconstitution
Key attributes
Kit contents
- 1 × TB-500 5mg vial
- Tamper-evident flip-off cap
- Batch-tested for purity (≥99%)
- Lyophilized for stability during shipping
Each vial is intended for laboratory research use only and is not for human or veterinary use.
Research usage
How is TB-500 5mg used in research?
TB-500 is the research designation for a synthetic peptide derived from thymosin β4, a naturally occurring actin-sequestering protein. In preclinical models it is investigated for its capacity to bind and regulate G-actin, a mechanism implicated in cytoskeletal dynamics and cell motility. Researchers study the peptide as a probe for cell migration, endothelial differentiation, and angiogenesis in cultured systems. It is also examined in laboratory wound-healing and tissue-repair paradigms, where actin regulation is thought to influence cellular recruitment. Further investigations explore its interactions with pathways governing inflammation and extracellular-matrix remodeling. All such work is conducted strictly within controlled laboratory settings.
Research reports that thymosin β4-derived peptides promote endothelial cell migration and tube formation in cultured assays. In animal research models of dermal and corneal injury, studies describe accelerated closure and increased vascularization associated with peptide exposure. Preclinical cardiac-injury investigations have reported changes in cell survival and myocyte organization following administration in rodent models. Additional reports note modulation of inflammatory markers and collagen deposition during tissue-repair studies. These observations remain confined to experimental research contexts and have not been established for any clinical application.
The safety profile of TB-500 has not been completely characterized and its effects in humans are unknown. It should be handled only by qualified personnel using appropriate laboratory protective equipment and standard handling procedures. This material is supplied strictly for in-vitro and preclinical research and is not for human or veterinary use. Reconstituted or dry material should be kept away from unauthorized access and disposed of in accordance with institutional guidelines.
Recommended ratio
- 2 mL of bacteriostatic water per 5 mg vial
- Equivalent to 2.5 mg/mL (i.e. 0.25 mg per 10 units on a 100 U insulin syringe)
- Disinfect the vial stopper with an alcohol swab and allow it to dry.
- Inject the bacteriostatic water slowly down the inner wall of the vial.
- Gently swirl — do not shake — until the powder is fully dissolved, then store as directed below.
Unopened / before reconstitution
- Store refrigerated (2 °C – 8 °C), away from light and moisture.
- For long-term storage, keep frozen (−20 °C); the lyophilized powder remains stable for extended periods.
Reconstituted solution
- Store refrigerated (2 °C – 8 °C) and use within 2–4 weeks.
- Avoid repeated freeze–thaw cycles; aliquot if longer storage is required.
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