MOTS-c
MOTS-C 20mg
$91.50
MOTS-c
MOTS-C 10mg
For in vitro research only
A mitochondrial-derived peptide supplied as a 10 mg lyophilized vial for research into AMPK activation, metabolic homeostasis, and insulin sensitivity.
Third-party testedView certificate
$50.00
Size
10mg20mg
Quantity
1
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Technical specification
- Molecular formula
- -
- Molar mass
- 2174.6 g/mol
- Purity
- ≥99%
- Synonyms
- Mitochondrial ORF of the 12S rRNA type-c
- Solubility
- Water-soluble (reconstitute with bacteriostatic water)
- Organoleptic profile
- White to off-white lyophilized powder
- Composition
- Synthetic peptide - requires reconstitution
Key attributes
Kit contents
- 1 × MOTS-C 10mg vial
- Tamper-evident flip-off cap
- Batch-tested for purity (≥99%)
- Lyophilized for stability during shipping
- Bacteriostatic water (3 mL)
Each vial is intended for laboratory use only.
Research usage
How is MOTS-C 10mg used in research?
MOTS-c is a mitochondrial-derived peptide of 16 amino acids encoded within the mitochondrial 12S rRNA region. In preclinical research models it is studied as a regulator of cellular energy metabolism and is reported to translocate to the nucleus under metabolic stress to influence gene expression. Research indicates that MOTS-c is associated with activation of the AMPK pathway, a central sensor of cellular energy balance. It is investigated as a potential modulator of metabolic homeostasis and insulin sensitivity in laboratory settings.
Research reports that MOTS-c activates the AMPK signaling pathway and modulates metabolic flux in animal and cellular research models. Preclinical studies have investigated its association with glucose regulation, enhanced insulin sensitivity, and resistance to diet-induced metabolic changes in rodent models. It has also been studied for its reported influence on exercise capacity and cellular stress responses. These properties have positioned MOTS-c as a subject of interest in metabolic and cellular-energy research models.
The safety profile of MOTS-c has not been fully characterized in research models, and its long-term effects remain under investigation. It is intended strictly for in-vitro and laboratory research and should be handled only by qualified personnel using appropriate protective equipment. As with all research peptides, it must be kept away from any human or veterinary exposure. No safety conclusions for non-research applications should be drawn from the available data.
Recommended ratio
- 1 mL of bacteriostatic water per 10 mg vial
- Equivalent to 10 mg/mL (i.e. 1 mg per 10 units on a 100 U insulin syringe)
- Remove the plastic flip-off lid from the vial.
- Disinfect the rubber stoppers with alcohol wipes.
- Inject the diluent slowly down the inner wall of the vial to avoid foaming.
- Gently swirl the vial (never shake). Let it dissolve for about 10 minutes.
Unopened / before reconstitution
- Store at a stable temperature.
- Stable for 24 months.
- For long-term storage (2+ years), store at -20 °C.
Reconstituted solution
- Must be kept refrigerated.
- Avoid exposure to light and excessive heat.
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